TABLE 2.
Nucleotide polymorphisms in DEN-2 virus E protein gene clones
| Source | No. of clones | No. with consensus sequence | No. of clones with indicated no. of nucleotide changes
|
No. of stop codons | No. of sites at which nucleotides varied | dN/dSa | Mean diversity (%)b | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | |||||||
| Human Myanmar. 32309/98 | 14 | 4 | 2 | 4 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 21 | 0.85 | 0.12 |
| Human Myanmar. 35004/99 | 12 | 1 | 4 | 3 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 23 | 2.0 | 0.15 |
| Human Myanmar. 36273/00 | 11 | 2 | 1 | 1 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 30 | 1.0 | 0.21 |
| Mosquito Myanmar. 196/00 | 20 | 0 | 2 | 3 | 1 | 3 | 3 | 5 | 2 | 1 | 0 | 0 | 0 | 17 | 48 | 0.58 | 0.31 |
| Mosquito Myanmar. 025/00 | 20 | 5 | 1 | 0 | 2 | 1 | 1 | 3 | 1 | 3 | 2 | 0 | 1 | 4 | 46 | 0.74 | 0.32 |
| Mosquito Myanmar. 376/00 | 17 | 1 | 2 | 0 | 3 | 1 | 5 | 3 | 0 | 0 | 1 | 0 | 1 | 4 | 47 | 0.69 | 0.29 |
| Isolate Myanmar. 376/00 | 20 | 5 | 4 | 3 | 0 | 5 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 6 | 33 | 0.82 | 0.20 |
a
Ratio of nonsynonymous to synonymous nucleotide changes.
b
Number of substitutions divided by the number of nucleotides sequenced times 100.