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Electron micrographs of negatively stained KOS capsids. Infected-cell lysates were sedimented through sucrose gradients, and the capsids in the fractions were stained prior to electron microscopy. The gradients were fractioned from the bottom up. Shown in panel A are capsids (mixture of A and B capsids) present in fraction 9 (F9) of the gradient. C capsids (B) were present in fraction 4 (F4) of the gradient. Bars, 100 nm.
