Table 1.
Oligopeptides derived from R1 and comparison of the sequences with R1 from other species
Species | Amino acid no. | Peptide name | Sequences |
---|---|---|---|
Mouse | 5–17 | RNR-N | KRDGRQERVMFDK(C) |
Human | 5–17 | RNR-N | KRDGRQERVMFDK(C) |
S. pombe | 5–17 | KRDGRQEKVAFDK | |
Mouse | 572–583 | M572 | NVAPTDLWDWKP |
Human | 572–583 | NVTPTDLWDWKV | |
S. pombe | 571–582 | PM1 | NVNPTDLWDWAE(C) |
571–582 | PM1B | NVNPTDLWDWAE | |
Xenopusa | X384 | NVTPTDLWDWTA | |
Mouse | 754–772 | KEKLKDKEKALKEEEEKER | |
Human | 754–772 | RNR-C | (C)KEKLKDKEKVSKEEEEKER |
S. pombe | 753–771 | PVALRARNEESNEENKKPV | |
Mouse | 783–792 | M783 | NREECLMCGS |
Human | 783–792 | NRDECLMCGS | |
S. pombe | 802–811 | NPEACEMCSA |
The amino acid sequence of Xenopus R1 was deduced from the nucleotide sequence of a PCR fragment that lacks amino- and carboxyl-terminal portions of R1 (see MATERIALS AND METHODS).