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The effect of increased cellular cholesterol on different transport steps. An overview of recent findings
| Transport step | Protein/lipid followed | Effect of increased cholesterol | Reference |
|---|---|---|---|
| Plasma membrane to Golgi apparatus | Lactosylceramide (LacCer) | LacCer targeted to endosomes/lysosomes rather than to the Golgi complex. | (Puri et al., 1999) |
| Late endosomes to TGN | IGF2/MPR | Transport to TGN is inhibited. | (Kobayashi et al., 1999) |
