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. 2000 May;2(3):208–225. doi: 10.1038/sj.neo.7900073

Figure 6.

Figure 6

A p53 autoregulatory feedback loop. Following accumulation, p53 can direct the inhibition of its own transcription by an indirect mechanism and inhibition of its own translation by binding to the 3′ UTR of the p53 mRNA.