Table 3.
Effect of cytochalasin D on membrane resealing in low Ca2+ Ringer's solution
| Condition | Resealing (%) | Resealing ratea | n |
|---|---|---|---|
| DMSO (control) | 25 | 0.003 ± 0.002 | 12 |
| 20 μM Cytochalasin D | 76.5 | 0.03 ± 0.007 | 17 |
Cells were treated with DMSO or 20 μM cytochalasin D for 1 h and wounded. Membrane sealing was monitored by photometric measurement of fura-2 fluorescence and visual inspection (see MATERIALS AND METHODS).
a
The resealing rate was defined as the inverse of the resealing time in seconds. For cells that failed to reseal, the rate was defined as zero. Values are mean ± SE.