Table 1.

Colony Formation in Soft Agar.

8-Cl-adenosine (µM)
	Control	0.05	0.5	1	2.5	5
HCT116	16.4±4.9	12.3±1.2	12.2±1.6	6.8±0.4*	5.4 ±1.0*	6.8±0.4*
HCT116E6	20.8±0.9	15.8±0.3	17.3±0.9	16.0 ±1.4	12.9±0.6†	9.3±2.9†
80S14	17.8±1.7	16.4±1.5	13.8±1.3	12.2±1.9*	6.4±0.9†	2.8±0.4†

Each colorectal cancer cell line was treated with 8-Cl-adenosine at the indicated concentrations in soft agar. Colonies were counted using light microscopy as described in Materials and Methods. Data represent the average±SEM of three experiments done in duplicate.

^*p<0.05;

^†p<0.005 when compared to control-treated cells.