Table 3.
Molecular Cytogenetic Changes and Disease Outcome Data for RMS-A.
| Year Diagnosed | Amplification | Other Gains | Live/Dead | Disease/Duration of Remission | |
| (Patient #) | MYCN | DDX1 | |||
| 1989 (A1)ρ | No | No | +11; +12q13-21 | D | Progressive |
| 1991 (A2) | No | No | +12q13-21* | D | Progressive |
| 1989 (A3) | Yes; 13x | Yes | +11p | D | 7 |
| 1990 (A4)ρ | No | No | +11; +12; +17q22-qter* | CCR | Disease free |
| 1986 (A5) | Yes; 11x | Yes | +11p15 | D | 1 |
| 1982 (A6)ρ | Yes; 5x | Yes | +11; +12 | D | Progressive |
| 1994 (A7)ρ | Yes; 20x | Yes | D | 6 | |
| 1994 (A8)ρ | Yes; 6x | Yes | +12q13-21 | D | 4 |
| 1994 (A9)ρ | No | No | +11p; +12q13-21; +17 | CCR | Disease free |
| 1993 (A10) | No | No | D | Progressive | |
| 1980 (A11) | No | No | D | Progressive; 24 | |
*
Denotes amplification.
CCR, complete clinical remission; D, dead.
ρ
-t(2,13) positive.