Table 1.
Cell Cycle Distribution of UV-Irradiated Normal and Li-Fraumeni Syndrome Cells.
| Cells | G1 | S | G2/M | ||||||
| C* | UV | Ratio | C | UV | Ratio | C | UV | Ratio | |
| NF | 68±2† | 59±5 | 0.87 | 18±1 | 21±4 | 1.17 | 14±1 | 20±3 | 1.43 |
| 041wt/mut | 43±0 | 36±1 | 0.84 | 33±2 | 41±4 | 1.24 | 23±2 | 24±3 | 1.04 |
| 087wt/mut | 59±5 | 52±1 | 0.88 | 28‖6 | 27±1 | 1.29 | 20±4 | 21±2 | 1.05 |
| 041mut | 55±7 | 25±2 | 0.45 | 21±0 | 56±5 | 2.00 | 17±3 | 19±4 | 1.12 |
| 087mut | 43 | 28 | 0.65 | 24 | 22 | 0.92 | 33 | 50 | 1.52 |
*
C, unirradiated control; UV, treated with 10 J/m2; ratio=% UV treated to % control.
†
Percentage of cells in the indicated phase of the cell cycle (± standard error).