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Aspirin induced caspase activation in HeLa cells. HeLa cells were treated with 1 and 5 mM of ASA for 24 hours. Western blotting of whole cell extracts demonstrated cleavage of procaspase 3 into its active subunit p17, and cleavage of caspase substrates PARP and PKC-δ into their proteolytic fragments p85 and p40 with 5 mM aspirin.
