Figure 5.
Kinetics of tumor growth and neovascularization. Halofuginone treatment began 7 days after tumor implantation (arrow). Tumor volume (A) and AVD (B) were measured from GE images at different days after tumor implantation. Control (filled circles, n=3) and oral administration of halofuginone (open circles, n=3). Note the arrest in tumor growth and regression of vascularization for mice treated with halofuginone.