Figure 8.

Panel A, effect of troglitazone on expression of A-FABP in bladder cancer cells. Cells were treated with troglitazone (10 µM) for 7 days and mRNA expression was determined by RNase protection. Lane 1, probes for β-actin and A-FABP, vehicle alone, Lane 2, troglitazone (10 µM). Total RNA (5 µg) was used for detection and the β-actin was the control for the amount of loaded RNA. Panel B, in situ hybridization showing distribution of A-FABP mRNA (white grains) in normal uroepithelial cell layer (original magnification, x40, top panel) and in submucosal infiltrating bladder cancer cells (original magnification, x400, lower panel).