Table 2.

Cytotoxicity of IAABE against Different Tumor Cells.

Human Tissue Type	Cell Line	Cytotoxicity (µg/ml)
		ID50	ID90
T-cell leukemia	CEM	0.047±0.011	0.1±0.007
Myelodysplasia syndromes	Sp	0.085±0.02	0.25±0.02
Melanoma	DND-1A	0.25±0.08	0.51±0.04
Renal cancer	786-0	0.042±0.006	0.08±0.01
Breast cancer	MCF-7	0.12±0.02	0.49±0.05
Non-small cell lung cancer	NCl-H522	0.05±0.01	0.09±0.01
Colon cancer	HCT-116	0.09±0.02	0.41±0.05
Lymphoma	Daudi/wt*	0.007±0.001	0.05±0.025
Lymphoma	Daudi/MDR*	0.005±0.001	0.06±0.004
Normal lymphocytes	PHA stimulated†	2.5±0.3	5.5±0.6

^*Daudi/MDR are PGP(+) cells, and Daudi/wt are PGP(-) cells [13].

^†Normal human lymphocytes were pretreated with 1 µg/ml phytohemagglutinin for 24 hours at 37°C to induce proliferation.

NOTE. ID₅₀ and ID₉₀, see Table 1 for definitions, and Refs. [12,13,42,43] for cell line origins.