Table 5.

Previously reported transcription factor binding sites in the PI3 promoter.

Transcription factor						Evidencec
Gene Symbol	Alias	Positiona	AL049767.12b	Author	PubMedID	IS	E	DM
NFKB1	NFκB		48564–48581	King et al. 2003	14521952	+
				Pol et al. 2003	12542536	+		+
		-479 – -470	49058–49067	King et al. 2003	14521952	+
		-340 – -331	49197–49206	King et al. 2003	14521952	+
		-164 – -153	49373–49384	Zhang 1995	7780965	+		+
				Bingle et al. 2001	11472979		+	+
				King et al. 2003	14521952	+
				Pol et al. 2003	12542536	+		+
JUN	AP1	-545 – -537	48992–49000	Zhang 1995	7780965	+		+
				Zhang 1997	9377579		+	+
				King et al. 2003	14521952	+
				Pol et al. 2003	12542536	+		+
		-356 – -345	49181–49192	Sallenave et al. 1994	7946401	+
				Pol et al. 2003	12542536	+		+
SP1		-82 – -74	49455–49463	Zhang 1995	7780965	+		+
				Pol et al. 2003	12542536	+		+
CEBPB	NFIL6	-386 – -378	49151–49159	Pol et al. 2003	12542536	+		+
		-356 – -345	49181–49192	Pol et al. 2003	12542536	+		+
		-307 – -299	49230–49238	Pol et al. 2003	12542536	+		+
		-203 – -194	49334–49343	Sallenave et al. 1994	7946401	+
				Pol et al. 2003	12542536	+		+
		-126 – -117	49411–49420	Pol et al. 2003	12542536	+		+
OCT1		-590 – -582	48947–48955	Zhang 1995	7780965	+		+
EST1	PEA-3	-484 – -479	49053–49058	Sallenave et al. 1994	7946401	+

^aPosition is given relative to ATG.

^bWe have mapped the location used in the studies to the current GenBank sequence to standardize the numbering between all studies.

^cIS, in silico; E, EMSA; DM, deletion mapping.