Skip to main content
. 2006 Apr 3;7:186. doi: 10.1186/1471-2105-7-186

Table 3.

Standard deviations of elementary mode fluxes under variation of single kinetic parameters, and elasticity coefficients of parameters at the experimental steady state

Enzyme Parameter EM1 EM2 EM3 EM4 EM5 EM6 EM7 EM8 Elasticity
GLK Vmax 0 0 0 0 0.12 0 0.58 4.01 1.0
Keq 0 0 0 0.21 0.48 0 1.85 8.94 0.0014
Km·Glc 0 0 0 0.23 0.58 0 2.30 12.02 -0.456
Km·G6P 0 0 0 0.21 0.52 0 1.99 9.80 0.015
Km·ATP 0 0 0 0 0.05 0 0.27 1.91 -0.283
Km·ADP 0 0 0 0 0.06 0 0.31 2.15 0.241
PGI Vmax 0 0 0 0.27 0.62 0 2.30 10.12 1.0
Keq 0 0 0 0 0.05 0 0.27 1.90 0.533
Km·G6P 0 0 0 0 0.04 0 0.21 1.48 -0.651
Km·F6P 0 0 0 0 0.04 0 0.01 0.02 0.178
PFK Vmax 0 0 0 0.09 0.29 0 1.17 6.27 1.0
gR 0 0 0 0 0.01 0 0.05 0.32 0.937
L0 0 0 0 0 0.10 0 0.50 3.53 -0.460
Km·ATP 0 0 0 0 0 0 0.01 0.06 -0.086
Km·F6P 0 0 0 0 0.05 0 0.26 1.80 -0.934
KAMP 0 0 0 0 0 0 0.02 0.15 -0.504
KATP 0 0 0 0 0 0 0.01 0.06 0.187
KF2bP 0 0 0 0 0.01 0 0.03 0.18 -0.626
KF16bP 0 0 0 0 0 0 0.02 0.16 0.401
ALD Vmax 0 0 0 0 0 0 0 0.03 1.0
Keq 0 0 0 0 0 0 0.02 0.13 1.499
Km·F16P 0 0 0 0 0 0 0.01 0.09 -0.398
Km·GAP 0 0 0 0 0 0 0.01 0.10 0.0067
Km·DHAP 0 0 0 0 0 0 0.02 0.11 0.094
Km·GAPi 0 0 0 0 0 0 0 0.01 0.0020
G3PDH Vmax 0 0 0.87 1.96 1.24 0 7.65 13.74 1.0
Keq 0 0 0 0 1.40 0 6.98 8.90 0.0016
Km·DHAP 0 0 0 0.38 1.60 0 8.77 11.88 -0.382
Km·NADH 0 0 0 1.87 1.28 0 8.50 13.81 -0.579
Km·NAD 0 0 0 0.39 1.57 0 8.65 11.80 0.362
Km·Gly 0 0 0 0 1.39 0 6.94 8.88 0.050
GAPDH Vmax 0 0 0 0.17 1.35 0 6.98 9.49 1.0
Keq 0 0 0 0.10 1.25 0 6.37 8.66 0.880
Km·GAP 0 0 0 0.12 1.48 0 7.58 10.23 -0.919
Km·BPG 0 0 0 0 0.17 0 0.83 1.16 0.082
Km·NAD 0 0 0 0.17 0.31 0 1.81 2.79 -0.145
Km·NADH 0 0 0 0.15 0.30 0 1.67 2.53 0.092
PGK Vmax 0 0 0 0.02 0.23 0 1.17 1.70 1.0
Keq 0 0 0 0.02 0.28 0 1.44 2.06 2.909
Km·BPG 0 0 0 0 0.02 0 0.11 0.16 0.062
Km·P3G 0 0 0 0.17 0.16 0 1.13 1.87 -0.623
Km·ADP 0 0 0 0.06 0.18 0 1.07 1.63 0.408
Km·ATP 0 0 0 0.15 0.18 0 1.17 1.90 -0.471
PGM Vmax 0 0 0.56 0.77 0.70 0 2.35 9.51 1.0
Keq 0 0 0 0.06 0.29 0 1.56 2.28 1.959
Km·P3G 0 0 0 0 0.25 0 1.27 1.81 -0.840
Km·P2G 0 0 0 0.18 0.27 0 1.63 2.57 0.302
ENO Vmax 0 0 0 0 0.03 0 0.14 0.19 1.0
Keq 0 0 0 0.10 0.27 0 1.48 2.22 0.325
Km·P2G 0 0 0 0.06 0.28 0 1.50 2.19 -0.506
Km·PEP 0 0 0 0.25 0.27 0 1.75 2.87 0.065
PYK Vmax 0 0 0 0 0.08 0 0.40 0.56 1.0
Keq 0 0 0 0.23 0.28 0 1.76 2.85 0.036
Km·PEP 0 0 0 0 0.16 0 0.82 1.15 -0.728
Km·Pyr 0 0 0 0 0.15 0 0.73 1.02 0.210
Km·ADP 0 0 0 0 0.17 0 0.84 1.19 -0.523
Km·ATP 0 0 0 0 0.02 0 0.08 0.13 0.327
PDC Vmax 0 0 0 0 0 0 0.02 0.02 1.0
Km·Pyr 0 0 0 0 0.02 0 0.09 0.13 -0.411
ADH Vmax 0 0 0 0.05 0.37 0 1.94 2.70 1.0
Keq 0 0 0 1.26 1.33 0 7.80 11.76 -3.393
Km·Ace 0 0 0.76 1.53 0.61 0 1.61 5.80 0.139
Km·Et 0 0 1.00 1.77 0.79 0 1.72 7.84 -0.457
Km·NADH 0 0 0 0.37 0.23 0 1.54 2.62 -0.113
Km·NADP 0 0 0.97 1.84 0.83 0 1.74 7.24 -0.102