Coprecipitation of Ypt1 and Ypt31/32 With GST-Bet3
and TRAPP. (a) GST-Bet3p or GST were expressed in yeast cells and
purified using GA. Equal volumes of eluted preps were analyzed by
SDS-PAGE followed by western blotting using anti-Ypt1 (top panel) or
Ypt31/32 (lower panel) antibodies. Ypt1 and Ypt31/32 proteins
coprecipitate only with GST-Bet3p but not with GST alone. (b) Superdex
200 column fractions containing GST-Bet3, high MW (fraction 30), low MW
(fractions 46–48), and the GST-Bet3 fraction that was loaded on the
column (L), were analyzed by SDS-PAGE followed by western blotting
using anti-Ypt1 (top panel), Ypt31/32 (middle panel), or anti-GST
(lower panel) antibodies. Ypt1 and Ypt31/32 proteins coprecipitate only
with the High MW but not with the Low MW GST-Bet3p.