Figure 1.

Effects of DGAT1 deficiency on fur appearance, water repulsion, and thermoregulation in mice. (a) Dry fur and hair loss in a 16-week-old male Dgat^–/– mouse. (b) Male Dgat^+/+ and Dgat^–/– mice 5 minutes after water immersion. (c and d) Impaired water repulsion and thermoregulation in Dgat^–/– mice after water immersion. Dgat^–/– mice retained more water in their fur than did Dgat^+/+ mice, as reflected by a greater increase in mean relative body weight (c). Dgat^–/– mice also developed hypothermia (d). n = 4 per genotype. *P < 0.05.