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. 2002 Jan 15;109(2):269–276. doi: 10.1172/JCI13997

Figure 5.

Figure 5

GalNAc-4-SO4–specific binding is reduced in membranes from M/G4S-R+/– mice as compared with M/G4S-R+/+ mice. Membranes were prepared from livers of three M/G4S-R+/+ and three M/G4S-R+/– mice and tested for binding of S4GGnM-BSA by the Man/GalNAc-4-SO4 receptor and ASOR by the asialoglycoprotein receptor in triplicate at three different concentrations of membranes. The results are presented as cpm bound per microgram of membrane protein. The difference between the mean of 31.3 cpm bound per microgram for M/G4S-R+/+ mice and 20.8 cpm bound per microgram for M/G4S-R+/– mice for S4GGnM-BSA was highly significant (P = 0.0009), whereas the difference between the mean of 279 cpm bound per microgram for M/G4S-R+/+ mice and 298 cpm bound per microgram for M/G4S-R+/– mice for ASOR was not significant (P = 0.58).