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. 2002 Feb 1;109(3):373–381. doi: 10.1172/JCI13779

Figure 3.

Figure 3

Heart failure of lpr mice in response to pressure overload. (a and b) Representative, superimposed, steady-state pressure-volume loops of a wild-type (black) or lpr mouse (gray) 2 days after sham-operation (a) or abdominal aortic banding (b). (c and d) Representative pressure-volume loops during transient reduction of cardiac preload 2 days after sham-operation (c) or abdominal aortic banding (d). (e and f) Echocardiographic measurements of surviving wild-type (WT) and lpr mice 14 days after induction of pressure overload. The mean ± SEM from six mice per group is shown. *P < 0.05 for aortic banding versus control. LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter.