Figure 2.

(a) Changes from baseline in CD4⁺ T cell percentages during the first 28 days of follow-up in patients belonging to the CsA + HAART cohort (n = 9) and to the HAART only cohort (n = 29). Student t test P values of comparisons between the two treatment cohorts were: P = 0.048 at day 7, P = 0.018 at day 14, and P = 0.009 at day 28. (b) Changes from baseline in CD4⁺ T cell counts (cells/μl) during the first 28 days of follow-up in patients of the two treatment cohorts. Student t test P values of comparisons between the two treatment cohorts were: P = 0.027 at day 7, P = 0.05 at day 14, and P = 0.017 at day 28. Data are presented as mean ± SEM, and a two-tailed P value less than 0.05 was considered significant (a and b). (c) Changes over time in CD4⁺Ki-67⁺ T cell percentages during the first 28 days of follow-up in two representative patients belonging to the CsA + HAART cohort. (d) Correlation between baseline plasma HIV-1 RNA levels and changes from baseline in CD4⁺ T cell counts at week 2 in the nine patients in the CsA + HAART cohort (r = 0.85, P = 0.004). Plasma HIV-1 RNA levels are expressed as log₁₀ copies/ml, and the number of CD4⁺ T cells is expressed in cells/μl. The regression line is shown. A two-tailed P value less than 0.05 was considered significant.