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. 2002 Apr 15;109(8):1111–1120. doi: 10.1172/JCI14255

Figure 4.

Figure 4

Reduced anti-AChR IgG response in DQ6 mice compared with DQ8, DR3, and DQ8×DR3 F1 mice. Serum individually derived from DQ6, DQ8, DR3, and DQ8×DR3 F1 mice (eight mice of each group) on days 15, 45, and 75 after the first H-AChR immunization was measured for anti–mouse muscle AChR IgG level by α-BTX radioimmunoassay. The mean value of cpm of prebleeding serum from all transgenic mice was similar (DQ8, 396 ± 55; DR3, 414 ± 47; DQ6, 390 ± 30; DQ8×DR3 F1, 400 ± 47). The error bars are SE. *P < 0.01 and **P < 0.05, Student’s t test.