sAC is a single copy gene preferentially
expressed in testis. (A) Southern blots of 10 μg rat
genomic DNA digested with BamHI (B),
EcoRI (E), HindIII (H), and
XhoI (X) probed at high (Left) or low
(Right) stringency by using the 1-kb PCR-generated sAC
fragment containing both presumptive catalytic domains. (B)
Rat multiple tissue Northern blot (CLONTECH) representing approximately
2 μg poly-A+ RNA from testis (T), kidney (K), skeletal
muscle (Sk), liver (Li), lung (Lu), spleen (S), brain (B), and heart
(H) probed with 1-kb PCR-generated sAC fragment (Upper)
or with actin control (Lower). The sAC transcript is
approximately 5.3 kb and, in most tissues, actin is approximately 2.0
kb.