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. 2002 Jun 1;109(11):1405–1415. doi: 10.1172/JCI15681

Figure 9.

Figure 9

COX-2 regulates cbfa1 and osterix in bone marrow stromal cell cultures. Bone marrow stromal cells from four wild-type or COX-2–/– mice were pooled and cultured as described previously. Total RNA was extracted on day 13 and real-time PCR was performed as described in the Methods. The relative expression of cbfa1 (a) and osterix (b) mRNA, standardized to actin, was determined as described in Methods and is presented as the mean ± SEM in log scale. Statistical significance compared with wild-type is indicated (*P < 0.05).