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. 2003 Mar 17;22(6):1381–1388. doi: 10.1093/emboj/cdg137

Table I. Summary of HPRT cDNA containing transposed TCRα signal ends.

  HPRT mutant
  F1 MFS6 M2
Subject    
 Sex Male Female
 Age 45 years Newborn
Insert length (bp) 369 347
TCRα V TCR V23 TCRα V35
 Nibbled nucleotidesa AGCA (91 267–91 270) AG (226 402–226 403)
TCRα J TCRα J48 TCRα J46
 Nibbled nucleotidesa TATCTAACTT (30 737–30 746) AGAAGA (33 647–33 652)
 N nucleotide insertions TTATTGAG GAAGAGG
TCR reading frame TGA in V-J junction TGA in J
HPRT reading frame TGA at new codon 11 TGA at new codon 16

aNucleotides in the TCRα region are numbered based on sequence data submitted to the DDBJ/EMBL/GenBank database under accession No. AE000660 for TCRα V21–35, and accession No. M94081 for TCRα J.