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. 1995 Oct;73(4):348–350. doi: 10.1136/adc.73.4.348

Nutritional care and candidates for small bowel transplantation.

S V Beath 1, I W Booth 1, M S Murphy 1, J A Buckels 1, A D Mayer 1, P J McKiernan 1, D A Kelly 1
PMCID: PMC1511354  PMID: 7492202

Abstract

Twenty two children were evaluated for small bowel transplantation between 1989 and 1994. Eight were unfit for transplantation and died within three months; a raised plasma bilirubin concentration (> 200 mumol/l) predicted death from liver failure within six months (p = 0.0001). The 11 children who were not managed by a multidisciplinary nutritional care team were less well nourished at referral, had more complications with intravenous feeding catheters, and greater early mortality while awaiting transplantation (p < 0.05). It is recommended that children with chronic intestinal failure be referred for assessment early, before liver dysfunction is established.

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Selected References

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  1. Amarnath R. P., Fleming C. R., Perrault J. Home parenteral nutrition in chronic intestinal diseases: its effect on growth and development. J Pediatr Gastroenterol Nutr. 1987 Jan-Feb;6(1):89–95. doi: 10.1097/00005176-198701000-00016. [DOI] [PubMed] [Google Scholar]
  2. Bisset W. M., Stapleford P., Long S., Chamberlain A., Sokel B., Milla P. J. Home parenteral nutrition in chronic intestinal failure. Arch Dis Child. 1992 Jan;67(1):109–114. doi: 10.1136/adc.67.1.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Calne R. Y., Sells R. A., Pena J. R., Davis D. R., Millard P. R., Herbertson B. M., Binns R. M., Davies D. A. Induction of immunological tolerance by porcine liver allografts. Nature. 1969 Aug 2;223(5205):472–476. doi: 10.1038/223472a0. [DOI] [PubMed] [Google Scholar]
  4. Capron J. P., Gineston J. L., Herve M. A., Braillon A. Metronidazole in prevention of cholestasis associated with total parenteral nutrition. Lancet. 1983 Feb 26;1(8322):446–447. doi: 10.1016/s0140-6736(83)91442-3. [DOI] [PubMed] [Google Scholar]
  5. Dollery C. M., Sullivan I. D., Bauraind O., Bull C., Milla P. J. Thrombosis and embolism in long-term central venous access for parenteral nutrition. Lancet. 1994 Oct 15;344(8929):1043–1045. doi: 10.1016/s0140-6736(94)91707-8. [DOI] [PubMed] [Google Scholar]
  6. Goulet O., Revillon Y., Brousse N., Jan D., Canion D., Rambaud C., Cerf-Bensussan N., Buisson C., Hubert P., de Potter S. Successful small bowel transplantation in an infant. Transplantation. 1992 Apr;53(4):940–943. doi: 10.1097/00007890-199204000-00046. [DOI] [PubMed] [Google Scholar]
  7. Grant D., Wall W., Mimeault R., Zhong R., Ghent C., Garcia B., Stiller C., Duff J. Successful small-bowel/liver transplantation. Lancet. 1990 Jan 27;335(8683):181–184. doi: 10.1016/0140-6736(90)90275-a. [DOI] [PubMed] [Google Scholar]
  8. Kelly D. A., Buckels J. A. The future of small bowel transplantation. Arch Dis Child. 1995 May;72(5):447–451. doi: 10.1136/adc.72.5.447. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kocoshis S. A. Small bowel transplantation in infants and children. Gastroenterol Clin North Am. 1994 Dec;23(4):727–742. [PubMed] [Google Scholar]
  10. Lillehei R. C., Idezuki Y., Feemster J. A., Dietzman R. H., Kelly W. D., Merkel F. K., Goetz F. C., Lyons G. W., Manax W. G. Transplantation of stomach, intestine, and pancreas: experimental and clinical observations. Surgery. 1967 Oct;62(4):721–741. [PubMed] [Google Scholar]
  11. Puntis J. W., Booth I. W., Buick R. Cisapride in neonatal short gut. Lancet. 1986 Jul 12;2(8498):108–109. doi: 10.1016/s0140-6736(86)91644-2. [DOI] [PubMed] [Google Scholar]
  12. Puntis J. W., Holden C. E., Smallman S., Finkel Y., George R. H., Booth I. W. Staff training: a key factor in reducing intravascular catheter sepsis. Arch Dis Child. 1991 Mar;66(3):335–337. doi: 10.1136/adc.66.3.335. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Reynolds A. P., Kiely E., Meadows N. Manganese in long term paediatric parenteral nutrition. Arch Dis Child. 1994 Dec;71(6):527–528. doi: 10.1136/adc.71.6.527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Sax H. C., Bower R. H. Hepatic complications of total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1988 Nov-Dec;12(6):615–618. doi: 10.1177/0148607188012006615. [DOI] [PubMed] [Google Scholar]
  15. Simkiss D. E., Adams I. P., Myrdal U., Booth I. W. Erythromycin in neonatal postoperative intestinal dysmotility. Arch Dis Child. 1994 Sep;71(2):F128–F129. doi: 10.1136/fn.71.2.f128. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Smallman S., Handy D., Puntis J. W., Booth I. W. The nutrition team in a children's hospital. Nutr Health. 1987;5(3-4):137–144. doi: 10.1177/026010608700500404. [DOI] [PubMed] [Google Scholar]
  17. Stein A., Hope T., Baum J. D. Organ transplantation: approaching the donor's family. BMJ. 1995 May 6;310(6988):1149–1150. doi: 10.1136/bmj.310.6988.1149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Tzakis A. G., Todo S., Reyes J., Abu-Elmagd K., Casavilla A., Ohya T., Fung J. J., Yunis E., Demetris A. J., Kocoshis S. Clinical intestinal transplantation: focus on complications. Transplant Proc. 1992 Jun;24(3):1238–1240. [PMC free article] [PubMed] [Google Scholar]
  19. Wood R. F., Clark C. L. Small bowel transplantation. BMJ. 1992 Jun 6;304(6840):1453–1454. doi: 10.1136/bmj.304.6840.1453. [DOI] [PMC free article] [PubMed] [Google Scholar]

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