Skip to main content
. 1999 Jan 5;96(1):185–190. doi: 10.1073/pnas.96.1.185

Figure 1.

Figure 1

Contemporary models for the activation of pTh cells. For a detailed explanation, see the text. The generation of signal 1 alone results in inactivation, whereas activation requires the generation of both signal 1 and signal 2 (costimulatory signal).