Table 1.
Sequence analysis of coding joints in s/+-ts and scid-ts cells
| Clone | Vκ | N/P | Jκ1 |
|---|---|---|---|
| GTGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC | |||
| (germline sequence) | |||
| S/+01 | (Vκ4)GGAGTAGTAA-4 | — | 3-GACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC |
| S/+02 | (Vκ23)ACAGCTGGCC-1 | — | 5-CGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC |
| S/+03 | (Vκ12)TGGGGTACTC-1 | — | 1-TGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC |
| S/+04 | (Vκ23)ACAGCTGGCC-1 | — | 1-TGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC |
| S/+05 | (Vκ28)AATTATCC-3 | — | 2-GGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC |
| S/+06 | (Vκ4)-12 | — | 12-GTGGAGGCACCAAGCTGGAAATCAAAC |
| ss01 | (Vκ1)ACACATCAGCCT | CC | GTGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC |
| ss02 | (Vκ4)GTTACCCACCCA | TGGG | 26-TGGAAATCAAAC |
| ss03 | (Vκ1)-25* | — | 22-AAGCTGGAAATCAAAC |
| ss04 | (Vκ12)-17 | — | 29-AATCAAAC |
| ss05 | (Vκ10)-32 | — | 27-GGAAATCAAAC |
| ss06 | (Vκ4)-18 | — | −48* |
| ss07 | (Vκ4)-21 | — | −53 |
| ss08 | (Vκ1)-53 | — | −51 |
| ss09 | (Vκ8)-52 | — | −74 |
| ss10 | (Vκ10)-19 | — | −158 |
*
The extent of nucleotide loss is indicated either by the number flanking the coding sequences or as −number, without coding sequences. N and P addition are shown in N/P, with P nucleotides underlined.