Figure 1.
Two conceptual approaches to screening glycan libraries. (a) When specific target cell types or glycoprotein ligands are known for a lectin, oligosaccharides released specifically from these sources can be separated by chromatography and examined by probing a relatively small array. (b) In the alternative 'glycomic' approach, a generic library of purified glycans produced synthetically and/or from natural sources can be screened with various different lectins.