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Memory T cells in JAK3 BMT mice. Spleen and lymph nodes were collected from HKx31-infected surviving mice at 130 days after challenge. ELISpot assay of pooled lymphocyte populations for IFN-γ SFC demonstrated the presence of substantial numbers of memory CD4+ and CD8+ T cells from both +/+ BMT (open bars) and JAK3 BMT (filled bars) mice. The background level of IFN-γ production after incubation with untreated stimulators was <33 SFC/106 cells.
