Table 2.

Mating-specific S. cerevisiae genes with orthologs in C. glabrata

Gene	Function
MFALPHA2	Mating pheromone α-factor
STE13	Peptidase, α-factor processing
STE6	Exporter of a-factor
FIG4	Lipid phosphatase, pheromone induced
FAR1	Inhibitor of Cdc28-Cln1/2 kinase complexes
CDC24	GTP-GDP exchange factor for Cdc42
SGV1	Kinase, pheromone adaptation
AKR1	Negative regulator in the pheromone response pathway
FUS3	Kinase, activates Ste12 and Far1
KAR5	Required for nuclear membrane fusion during karyogamy
LSG1	Required for normal morphology, mating and sporulation
OPY2	Overproduction causes insensitivity to α-factor arrest
SAG1	α-Agglutinin