Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Calcineurin selectively activates IL-1α expression. Porcine aortic endothelial cells were transfected with increasing amounts of a plasmid encoding constitutively-active calcineurin (ΔCaM-AI). Control cells were stimulated with IL-1α. After 12 hours the amounts of IL-1α, Eselectin and GAPDH mRNA were measured by RT-PCR. The results show that calcineurin activity selectively activates IL-1α expression.
