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. Author manuscript; available in PMC: 2006 Jul 19.
Published in final edited form as: Rev Sci Instrum. 2006 Feb;77(2):023702-1–023702-9. doi: 10.1063/1.2166509

FIG. 10.

FIG. 10

Chromatin extension: (a) Extension profile for three consecutive manipulations of the same chromatin fiber. For extensions where the maximum applied force was approximately 15 pN, no nucleosome disruption events were observed. In the subsequent traces (24 and 30 pN) the increased maximum force caused a total of four nucleosome disruption events [(c), 1–4], with possible multiple disruptions taking place in event 2. (b) Force profile corresponding to each extension in (a).