Figure 2.

Deduced protein sequence of FIS2. The amino acid sequence corresponding to the C₂H₂ zinc finger motif is double underlined. The three putative nuclear localization signals are underlined with thick lines. The 12 A repeats are shown in filled boxes and the 7 B repeats are shown in open boxes. The [T/S]PXX motifs within the A repeats are underlined with thin lines. The position of the fis2–1 (deletion of T) and the fis2–4 (G → A) mutations are shown with the resulting modifications of the encoded peptide. The location of the fis2–3 mutation (G → A) at the junction of intron 5 and exon 6 is indicated by an arrow (↓). Stop codons are indicated with asterisks (∗).