Figure 5.

Repeat of a structural motif within fold a.118. The color scheme is the same as in Figure 4. Structures of domains (a) d1a17_, (b) d1kula_ and (c) d1qbkb_ from fold a.118 (alpha-alpha superhelix, multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix). Domains have 159 residues and 7 helices, 211 residues and 10 helices, and 888 residues and 48 helices, respectively. The VAST similarity score Pcli assigned to the domain pair (a) and (b) is -2.3, to (a) and (c) is -3, and to (b) and (c) is -8. The SHEBA Zscores are respectively 1.8, 1.3, and 1.3. The negative values reported for the Pcli should be interpreted as values very close or equal to zero (no similarity), and resulted from the use of an approximation for the computation of Pcli.