Figure 3. Plasma from patients with complicated appendicitis inhibits the monocyte response to LPS in vitro. Cells were stimulated with 0.5 ng/mL LPS after exposure to acute plasma from patients with uncomplicated appendicitis (n = 11) or complicated appendicitis (n = 8). Cells exposed to plasma from the less severely ill patients released more IL-8 (12,100 ± 3,350 [SEM] pg/mL) than did cells exposed to plasma from patients with complicated disease (2,480 ± 440 pg/mL).