Figure 2. Microcirculation of normal exocrine pancreas and pancreatic carcinoma. (A) Normal pancreatic microcirculation represents a dense capillary network supplied by individual arterioles and drained by individual venules (white line, 25 μm). (B) Solid tumors are characterized by features such a low vessel density, lack of vascular differentiation, heterogeneous vessel distribution, and irregular vessel diameter (intravital plasma staining with FITC-labeled albumin; white line, 25 μm).