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Effect of in vivo 4PBA treatment on mitochondrial ultrastructure in adrenocortical cells from ALD mice. Adrenal glands were harvested from wild-type (A), ALD (B), and 4PBA-treated ALD (C) mice after perfusion with 4% glutaraldehyde. They were postfixed in osmium tetroxide and embedded in epoxy resin. The embedded tissues were thin sectioned and stained with uranyl acetate-lead citrate and examined under an electron microscope (magnification, ×48,750).
