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Time course of response to 4PBA. Fibroblasts from ALD mice were grown in medium containing 5 mM 4PBA for the times indicated. LCFA (C16:0) and VLCFA (C24:0) β-oxidation activities were measured, and values were expressed as fold increases relative to untreated-control values. 4PBA treatment (5 mM) increased LCFA (C16:0) before VLCFA (C24:0) β-oxidation in ALD mouse fibroblasts.
