TABLE 2.
Hematological profiles of age-matched wild-type and mdm2puro/Δ7-12 micea
| mdm2 genotype | No. | RBC (106/μl) | WBC (103/μl) | Neutrophils (103/μl) | Lymphocytes (103/μl) |
|---|---|---|---|---|---|
| +/+ | 6 | 8.2 (7.2-9.5) | 5.4 (3.5-7.3) | 0.5 (0.1-1.0) | 3.0 (2.7-3.4) |
| puro/Δ7-12 | 5 | 6.7 (6.3-7.5) | 1.6 (1.1-1.8) | 0.3 (0.1-0.4) | 1.1 (0.8-1.3) |
a
Total red blood cell (RBC) counts and total white blood cell (WBC) counts were determined with an Advia 120 automated hematology analyzer (Bayer). Total neutrophil and lymphocyte counts were calculated from the percentage of these leukocytes (manual differential count) and the total WBC count and are expressed as the average concentration (range).