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. 2002 Dec 1;110(11):1703–1716. doi: 10.1172/JCI15849

Figure 4.

Figure 4

KC/CXCL1 and MIP-2/CXCL2/3 mRNA levels are markedly elevated during VILI. (a) RT-PCR determination of KC/CXCL1 mRNA in lung homogenates from mice placed on either high– or low–peak pressure/stretch ventilator protocol, or from normal nonventilated mice. Semiquantitative results are expressed as a ratio of each PCR product to β-actin band density (n = 4 mice per group). *P < 0.02. (b) RT-PCR determination of MIP-2/CXCL2/3 mRNA in lung homogenates from mice placed on either high– or low–peak pressure/stretch ventilator protocol, or from normal nonventilated mice. Semiquantitative results are expressed as a ratio of each PCR product to β-actin band density (n = 4 mice per group). *P < 0.02.