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HBx induces COX-2 expression. (a) The expression of COX-2 and COX-1 was evaluated by Western blot in CMO, CMX, HepG2, 2.2.15, and 4pX cells (treated or not treated with tetracycline). (b) The presence of COX-2 mRNA was analyzed by quantitative RT-PCR in CMO and CMX cells, and in Chang liver cells transiently transfected with pSV-X or the control vector pSV-hygro.
