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Location of the translational silencing element in the human Cp 3′-UTR. (A) Folding structure of the full-length Cp 3′-UTR as determined by the mfold algorithm. The terminal positions of key constructs are indicated by boxes. (B) A summary of the activities of synthetic Cp 3′-UTR cRNA fragments as measured in a competition EMSA and in an in vitro translation assay in which the fragment was added as a decoy.
