FIG. 2.

Mean serum (solid line) and lung (dashed line) tigecycline concentrations in guinea pigs with L. pneumophila pneumonia. Animals were given a single 7.5-mg/kg dose administered by the subcutaneous route at time zero. Three animals were sampled at each time point except for the 24-h point, when two were sampled. One serum sample taken at 16.7 h contained no detectable drug. The error bars represent the ranges for the time points.