TABLE 1.
Characteristic | Value | Range |
---|---|---|
No. of patients | 49 | |
Gender (no. of patients) | ||
Men | 44 | |
Women | 5 | |
Median age (yr) | 45 | 28-57 |
Median HIV-1 RNA viral load (log10 no. of copies/ml) | 4.13 | 3-5.2 |
Median CD4 cell count (no. of cells/mm3) | 286 | 48-700 |
Median no. of PIs previously receiveda | 2 | 1-6 |
RTV | 15 | |
IDV | 43 | |
SQV | 6 | |
NFV | 30 | |
r/SQV | 24 | |
r/IDV | 6 | |
Median no. of PI resistance mutationsb | ||
Total (major + minor) | 6 | 1-10 |
Major | 2 | 0-4 |
Minor | 4 | 1-7 |
RTV, ritonavir; IDV, indinavir; SQV, saquinavir; NFV, nelfinavir; r/SQV, ritonavir plus saquinavir; r/IDV, ritonavir plus indinavir.
From the 2002 International AIDS Society table of resistance mutations (http://www.iasusa.org/resistance mutations/index.html).