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. 2002 Nov 15;110(10):1419–1427. doi: 10.1172/JCI15582

Figure 6.

Figure 6

Proteoglycan content is similarly reduced in cartilage of hTNFtg and c-fos–/–hTNFtg mice. Toluidine blue staining of articular cartilage was performed in hTNFtg (a), c-fos–/–hTNFtg (b), wild-type (c), and c-fos–/– mice (d). A marked reduction of proteoglycan content indicated by decreased staining intensity (green arrows) was found in hTNFtg and c-fos–/–hTNFtg mice. Asterisks indicate the joint space. AC indicates articular cartilage. Magnification: ×200.