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. 2003 Jan 1;111(1):121–128. doi: 10.1172/JCI15937

Figure 2.

Figure 2

The effects of various peptides on activation of PLA2 by TGase 2. (a) Purified PLA2 was preincubated with different amounts of TGase 2 for 15 minutes before assay. PLA2 activity was increased by incubation with TGase 2 in a dose-dependent manner. Data are presented as mean ± SD from three repeats of each TGase 2 concentration. (b) Purified PLA2 was preincubated with the peptides and 1 × 10–3 U TGase 2 for 15 minutes before assay. The recombinant peptide R2 markedly decreased PLA2 activity, although most AFs (A1–A3) and E3 inhibited PLA2 activity. Data are presented as mean ± SD from three separate experiments.