FIGURE 2 .

HER2 effects on cell speed and persistence. Cell migration of parental and 24H cells treated with EGF (100 ng/ml), HRG (80 ng/ml), or in serum-free conditions was recorded and quantified for (A) cell speed in μm/h, (B) directional persistence in minutes, and (C) diffusion constant in μm²/h. D shows inequalities at 95% confidence as evaluated using Kolmogorov-Smirnov test for nonnormal distributions. All data reported as mean ± SE. Number of cells per condition equals 153–196. (See Supplementary Methods and Supplementary Fig. 4 for raw data histograms.)