TABLE 14.

Oxidative phosphorylation parameters

Symbol	Value	Units	Description	Eq.	Refs.
ra	6.394 × 10−13	ms−1	Sum of products of rate constants.	A157	(16)
rb	1.762 × 10−16	ms−1	Sum of products of rate constants.	A158	(16)
rc1	2.656 × 10−22	ms−1	Sum of products of rate constants.	A157	(16)
rc2	8.632 × 10−30	ms−1	Sum of products of rate constants.	A157	(16)
r1	2.077 × 10−18		Sum of products of rate constants.	A157	(16)
r2	1.728 × 10−9		Sum of products of rate constants.	A157	(16)
r3	1.059 × 10−26		Sum of products of rate constants.	A157	(16)
ρres	3.0 × 10−3	mM	Concentration of electron carriers (respiratory complexes I-III-IV).	A157	(16)
Kres	1.35 × 1018		Equilibrium constant of respiration.	A159	(16)
ρres(F)	3.75 × 10−4	mM	Concentration of electron carriers (respiratory complexes II-III-IV).	A161	*
ΔΨB	50	mV	Phase boundary potential.	A157	(16)
G	0.85		Correction factor for voltage.	A157	(16)
Kres(F)	5.765 × 1013		Equilibrium constant of FADH2 oxidation.	A162	(16)
[FADH2]	1.24	mM	Concentration of FADH2 (reduced).	A162	(16)
[FAD]	0.01	mM	Concentration of FAD (oxidized).	A162	(16)
pa	1.656 × 10−8	ms−1	Sum of products of rate constants.	A163	(16)
pb	3.373 × 10−10	ms−1	Sum of products of rate constants.	A164	(16)
pc1	9.651 × 10−17	ms−1	Sum of products of rate constants.	A163	(16)
pc2	4.585 × 10−17	ms−1	Sum of products of rate constants.	A163	(16)
p1	1.346 × 10−8		Sum of products of rate constants.	A163	(16)
p2	7.739 × 10−7		Sum of products of rate constants.	A163	(16)
p3	6.65 × 10−15		Sum of products of rate constants.	A163	(16)
ρF1	1.5	mM	Concentration of F1F0-ATPase.	A163	(16)
KF1	1.71 × 106		Equilibrium constant of ATP hydrolysis.	A165	(16)
Pi	2.0	mM	Inorganic phosphate concentration.	A165	†
CA	1.5	mM	Total sum of mito adenine nucleotides.	A129	†
VmaxANT	0.025	mM ms−1	Maximal rate of the ANT.	A139	(16)
hANT	0.5		Fraction of ΔΨm.	A139	(16)
gH	1.0 × 10−8	mM ms−1 mV−1	Ionic conductance of the inner membrane.	A166	(16)
ΔpH	−0.6	pH units	pH gradient across the inner membrane.	A167	(16)
CPN	10.0	mM	Total sum of mito pyridine nucleotides.	A160	(16)
Cmito	1.812 × 10−3	mM mV−1	Inner membrane capacitance.	A123	(16)

^*The respiratory complex II carriers concentration was adjusted with respect to the value in Cortassa et al. (16) to match the reported range of oxygen consumption rates (0.04–0.5 mM s⁻¹ = 5–60 μMol O₂/min/mg) (1).

^†The total nucleotide level and inorganic phosphate were corrected with respect to previous publication (16) to follow reported experimental evidence (1,69).