Fig. 1.

Comparison of the zebrafish DrSINE3 transposable element and HsSINE3-1 as well as the orthologous conservation of HsSINE3-1 across various mammals. Related portions are shown in the same color. Most of the similarity between the human sequence and DrSINE3 lies within the central core region (shown in blue and labeled “B”); the best aligning portion of 162 bp in humans is indicated by the rectangle and shown as a pairwise alignment. For conservation across HDMR, colors are as follows: red, identical 4-way; black, nonidentical 4-way; gray, <4 bases align. The corresponding orthologous sequence in seven other mammals is shown as a multiple alignment in red.