TABLE 1.
Chromosomal location and putative function of four GAS genes
| Gene (spy no.)a | Chromosomal locationb | Putative function of encoded proteinc | LPXTG motifd |
|---|---|---|---|
| spy0747 | 607,542-610,274 | Extracellular nuclease | LPKTG |
| spy0843 | 694,643-697,669 | Cell surface protein | LPRTG |
| spy0872 | 718,489-720,501 | 2′,3′-Cyclic-nucleotide 2′-phosphodiesterase | LPITG |
| spy1972 | 1,639,165-1,642,662 | Pullulanase | LPKTG |
a
spy no. refers to the corresponding numerical identifier of each ORF as listed in GenBank.
b
The chromosomal location of each gene in the sequenced GAS M1 strain ATCC 700294 (11).
c
Putative function as determined by BLAST analysis.
d
Amino acid motif used to anchor proteins to the cell wall in gram-positive organisms. Single-letter amino acid abbreviations are used (L, leucine; P, proline; K, lysine; R, arginine; I, isoleucine; T, threonine; G, glycine).